Perioperative medicine & outcomes
Impact of hypotension prediction index-guided management on intraoperative hypotension and postoperative outcomes in abdominal surgery: A meta-analysis of randomized controlled trials
Authors' conclusion
HPI-guided management did not significantly improve patient-centered outcomes.
Study context
- Population
- Adults undergoing major abdominal surgery
- Participants
- 1,534 adults · 8 RCTs
- Comparison
- Hypotension Prediction Index (HPI)-guided management vs standard care
- Outcome
- Postoperative complications, AKI, perioperative mortality and hospital LOS
Methodological detailsrandom-effects models, post hoc analyses
- Random-effects models
- Post hoc analyses
Pooled result
As reported in the abstract
Postoperative complications, AKI, perioperative mortality and hospital LOS (primary outcomes)
Acute kidney injury (AKI), HPI-guided vs standard care: no significant difference
OR 0.85
95% CI 0.64–1.13
Postoperative complications, HPI-guided vs standard care: no significant difference
OR 1.10
95% CI 0.83–1.46
Mortality, HPI-guided vs standard care: no significant difference
OR 0.96
95% CI 0.32–2.83
Length of stay (LOS), HPI-guided vs standard care: no significant difference
SMD −0.15
95% CI −0.73 to 0.42
Further pooled results
| Outcome | Estimate |
|---|---|
| IOH metrics: TWA of MAP < 65 mmHg, AUT, total time with MAP < 65 mmHg (post hoc)HPI vs Standard care · TWA MAP < 65 mmHg · post hoc analysis | SMD −0.25 |
| IOH metrics: TWA of MAP < 65 mmHg, AUT, total time with MAP < 65 mmHg (post hoc)HPI vs Standard care · TWA MAP < 65 mmHg · post hoc analysis | MD −20.5 min |
| IOH metrics: TWA of MAP < 65 mmHg, AUT, total time with MAP < 65 mmHg (post hoc)HPI vs Standard care · AUT · post hoc analysis | SMD −0.83 |
| IOH metrics: TWA of MAP < 65 mmHg, AUT, total time with MAP < 65 mmHg (post hoc)HPI vs Standard care · total time with MAP < 65 mmHg · post hoc analysis | SMD −0.74 |
Intraoperative fluid use (post hoc)
- Fluid use, HPI-guided vs standard care: no significant difference
- SMD −0.06 (95% CI −0.35 to 0.24)
- Post hoc analysis
Original publication
Impact of hypotension prediction index-guided management on intraoperative hypotension and postoperative outcomes in abdominal surgery: A meta-analysis of randomized controlled trials. Anaesth Crit Care Pain Med. Published 30 October 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →