Organ support & nutrition

Impact of body mass index on 90-day survival in patients in cardiogenic shock treated with V-A extracorporeal membrane oxygenation (ECMO): A propensity weighted analysis

J Crit CarePublished Retrospective cohort study

Main finding · 90-day mortality (association with BMI)Result — go to the resultHazard ratio 0.99 95 % CI 0.97–1.01

Authors' conclusion

Patients with obesity treated with ECMO for refractory cardiogenic shock have similar 90-day outcomes to their lean counterparts, despite higher respiratory, renal, and device-related complications.

Study context

Population
Patients with refractory cardiogenic shock treated with V-A ECMO, two French ECMO centres, 2006–2022
Participants
921 patients
Exposure
Body mass index (BMI) and 90-day mortality
Outcome
90-day mortality
Follow-up
90 days
Methodological detailsinverse propensity-score weighted, propensity-score matched, multivariable models, prospectively maintained database, two centres
  • Inverse propensity-score weighted
  • Propensity-score matched
  • Multivariable models
  • Prospectively maintained database
  • Two centres

Main finding

90-day mortality (association with BMI)

Hazard ratio

0.99

95 % CI 0.97–1.01

P = 0.2

BMI
HR 0.99 (95 % CI 0.97–1.01); P = 0.2

As reported in the abstract

Observational data: associations, not effects.

Further findings

90-day mortality, ECPR subgroup (n = 204)

P = 0.5

Original publication

Impact of body mass index on 90-day survival in patients in cardiogenic shock treated with V-A ECMO: A propensity weighted analysis. J Crit Care. Published 11 October 2025. doi:10.1016/j.jcrc.2025.155284

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