Sex-Specific Obesity Paradox in Critically Ill Patients With Severe Acute Kidney Injury: A Retrospective Analysis
Authors' conclusion
There were sex differences in the association between BMI and mortality in critically ill patients with severe AKI.
Study context
- Population
- Critically ill patients with severe acute kidney injury (AKI) receiving continuous renal replacement therapy (CRRT), 8 tertiary hospitals in Korea2,308 male, 1497 female
- Participants
- 3,805 patients
- Exposure
- Body mass index (BMI) categories, by sex
- Outcome
- 90-day mortality
- Follow-up
- 90 days
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
Each group vs obeseHazard ratio (95% CI)P value
Underweightoverall population, adjusted
1.20(1.05–1.36)
P = 0.006Underweightmale patients, adjusted
1.30(1.10–1.53)
P = 0.002Normal weightmale patients, adjusted
1.18(1.04–1.35)
P = 0.010Observational data: associations, not effects.
Further findings
90-day mortality, subgroups of male patients (subgroup)
- Obesity paradox in male patients of old age, with septic AKI, or with low albumin levels
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Sex-Specific Obesity Paradox in Critically Ill Patients With Severe Acute Kidney Injury: A Retrospective Analysis. Crit Care Med. Published 9 December 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →