Cardiothoracic & vascular anesthesia
Impact of Covert Brain Infarction Following Coronary Angiography on Coronary Artery Bypass Surgery Outcomes
Authors' conclusion
Among patients undergoing elective CABG, there was no significant association between covert brain infarction following CAG and the occurrence of MACCEs within 30 days or long-term mortality after CABG.
Study context
- Population
- Patients undergoing preoperative coronary angiography (CAG) and brain magnetic resonance imaging (MRI) before elective coronary artery bypass grafting (CABG), single tertiary centre in Korea, 2006–20191,057 matched analysed
- Participants
- 2,476 patients
- Exposure
- Covert brain infarction after CAG vs none, before elective CABG
- Covert brain infarctionn = 212
- No covert brain infarctionn = 845reference
- Outcome
- Incidence of MACCEs
- Follow-up
- Within 30 days of CABG
Methodological detailssingle-centre, 1:4 propensity-score matched
- Single-centre
- 1:4 propensity-score matched
Main finding
As reported in the abstract
Each group vs no covert brain infarctionRisk difference (95% CI)
Covert brain infarction
−0.5(−5.6 to 4.4)
Each group vs no covert brain infarctionRelative risk (95% CI)P value
Covert brain infarction
0.97(0.66–1.32)
P = 0.85Observational data: associations, not effects.
Secondary outcomes
All-cause mortality · 5 years
p for stratified log-rank test = 0.33
Each component of major adverse cardiac and cerebrovascular events (MACCEs) · 30 days
- No significant differences in each component of MACCEs
Original publication
Impact of Covert Brain Infarction Following Coronary Angiography on Coronary Artery Bypass Surgery Outcomes. J Cardiothorac Vasc Anesth. Published 26 September 2024. doi:10.
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