Cardiothoracic & vascular anesthesia
Impact of early high flow nasal oxygen on diaphragmatic function and pulmonary complications after thoracic surgery: A randomized clinical trial
Authors' conclusion
Early HFNC support does not decrease the rate of postoperative diaphragmatic dysfunction rate or respiratory complications. In patients who develop postoperative diaphragmatic dysfunction, HFNC may play a role in mitigating the risk of PPCs.
Study context
- Population
- Patients undergoing video-assisted thoracoscopic lobectomy116 analysed
- Participants
- 58 vs 58
- Comparison
- High-flow nasal cannula (HFNC) vs conventional oxygen therapy after thoracic surgery
- HFNCn = 58
- Conventional oxygen therapy (COT)n = 58reference
- Primary endpoint
- Postoperative diaphragmatic dysfunction (diaphragmatic displacement <10 mm)
- Follow-up
- 2 and 24 h after surgery
Methodological detailssingle-centre, open-label
- Single-centre
- Open-label
Primary result
As reported in the abstract
Postoperative diaphragmatic dysfunction
P = 0.55
Further findings
PPCs within 7 days
P = 0.449
PPCs in patients with postoperative diaphragmatic dysfunction (subgroup) · post hoc
P = 0.037
| Outcome | OR (95 % CI) | |
|---|---|---|
| PPCs in patients with postoperative diaphragmatic dysfunction (subgroup)Post hoc mixed-model analysis · post hoc | 0.16 (0.02–0.83) | |
| 0.050.21520Odds ratio (log scale) |
Original publication
Impact of early high flow nasal oxygen on diaphragmatic function and pulmonary complications after thoracic surgery: A randomized clinical trial. J Clin Anesth. Published 23 July 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →