Cardiothoracic & vascular anesthesia
Impact of Noninvasive Ventilation Before and After Cardiac Surgery for Preventing Cardiac and Pulmonary Complications: A Clinical Randomized Trial
Primary resultResult — go to the resultRelative risk 0.69 95% CI 0.57–0.84Authors' conclusion
Our results indicate that the use of NIV before and after cardiac surgery reduces the rate of cardiopulmonary failure after high-risk cardiac surgery.
Study context
- Population
- Adults undergoing cardiac surgery at risk of postoperative cardiac or pulmonary failure
- Participants
- 216 adults
- Comparison
- Pre- and postoperative noninvasive ventilation (NIV) plus usual care vs usual care alone
- NIVn = 107
- No NIVn = 109reference
- Primary endpoint
- Composite of:
- Predefined
- Adjudicated cardiorespiratory failure
- Follow-up
- 1 month after cardiac surgery
Methodological detailsprospective, monocentric
- Prospective
- Monocentric
Primary result
As reported in the abstract
1 month
Relative risk
0.69
95% CI 0.57–0.84
P < 0.001
Events by treatment group
NIV vs No NIV
RR 0.69 (95% CI 0.57–0.84); P < 0.001
Further findings
Composite cardiorespiratory failure · 3 months
- Benefit persisted at 3 months
Intubation need and LOS in cardiac and pulmonary surgery ICUs and units
- No difference between the 2 groups
Original publication
Impact of Noninvasive Ventilation Before and After Cardiac Surgery for Preventing Cardiac and Pulmonary Complications: A Clinical Randomized Trial. Chest. Published 19 February 2025. doi:10.
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