Cardiothoracic & vascular anesthesia
Use of high‐flow nasal cannula versus other noninvasive ventilation techniques or conventional oxygen therapy for respiratory support following pediatric cardiac surgery: A systematic review and meta‐analysis
Authors' conclusion
High-flow nasal cannula is more effective in reducing the rate of postextubation failure compared to other forms of noninvasive ventilation techniques following surgery for congenital heart disease in pediatric-aged patients. high-flow nasal cannula is also associated with lower mortality rates and shorter length of stay. However, when comparing high-flow nasal cannula to conventional oxygen therapy, the findings were inconclusive primarily due to a limited number of scientific studies available on this specific comparison.
Study context
- Population
- Children undergoing cardiac surgery for congenital heart disease, after tracheal extubation
- Participants
- 1,565 children · 12 studies
- Comparison
- HFNC vs NIV or conventional oxygen therapy after extubation
- Outcome
- Tracheal reintubation (postextubation failure)
Pooled result
As reported in the abstract
Tracheal reintubation
Relative risk (95% CI)P value
HFNC vs Conventional oxygen therapy
0.67(0.24–1.90)
P = 0.46HFNC vs NIV
0.45(0.32–0.63)
P < 0.01Further pooled results
| Outcome | RR (95% CI) | P value | |
|---|---|---|---|
| MortalityHFNC vs NIV | 0.31 (0.16–0.61) | P < 0.01 | |
| 0.10.31310Relative risk (log scale) |
| Outcome | Mean difference (days) (95% CI) | P value | |
|---|---|---|---|
| Postoperative LOSHFNC vs NIV | −8.76 (−13.08 to −4.45) | P < 0.01 | |
| ICU LOSHFNC vs NIV | −4.63 (−9.16 to −0.11) | P = 0.04 | |
| −20−10010Difference, days (linear scale) |
Original publication
Use of high‐flow nasal cannula versus other noninvasive ventilation techniques or conventional oxygen therapy for respiratory support following pediatric cardiac surgery: A systematic review and meta‐analysis. Paediatr Anaesth. Published 22 February 2024. doi:10.
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