ICU sedation, delirium & recovery
Impact of sleep disturbances on outcomes in intensive care units
Authors' conclusion
Complete disappearance of REM sleep was significantly associated with poor clinical outcomes in critically ill patients.
Study context
- Population
- Conscious, non-sedated ICU patients: admitted for acute respiratory failure breathing spontaneously, under mechanical ventilation with weaning difficulties, or immediately after extubationor immediately after extubation 52
- Participants
- 131 participants · 3 pooled studies
- Comparison
- Complete disappearance of rapid eye movement (REM) sleep vs persistent REM sleep
- Outcome
- Poor clinical outcomes:
- Intubation after admission for acute respiratory failure
- Prolonged weaning under mechanical ventilation
- Reintubation after extubation
Methodological detailscomplete polysomnography
- Complete polysomnography
Pooled result
As reported in the abstract
Poor clinical outcomes
P = 0.03
Further pooled results
Deep sleep by timing of polysomnography
- Preserved in acute respiratory failure; markedly reduced under mechanical ventilation and after extubation
- P < 0.01
Atypical sleep
- Significantly more frequent under mechanical ventilation than breathing spontaneously
- P < 0.01
REM sleep
- Uncommon at any time of ICU stay
Original publication
Impact of sleep disturbances on outcomes in intensive care units. Crit Care. Published 9 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →