Impact on Anesthetic Agent Consumption After Autonomic Neural Blockade as Part of a Combined Anesthesia Protocol: A Randomized Clinical Trial
Primary result · Remifentanil consumptionResult — go to the resultMean difference −0.04 mcg/kg/min 95% CI −0.06 to −0.02Authors' conclusion
Performing ANB at the onset of LSG is a safe and effective approach that reduces remifentanil consumption and promotes hemodynamic stability during the procedure.
Study context
- Population
- Patients undergoing laparoscopic sleeve gastrectomy (LSG)included for analysis
- Participants
- 80 patients
- Comparison
- Autonomic neural blockade (ANB) at the onset vs at the end of LSG
- ANB at the onsetn = 40
- Controln = 40reference
- Primary endpoint
- Consumption of remifentanil and sevoflurane
Methodological detailsprospective, double-blinded, 2 high-volume institutions
- Prospective
- Double-blinded
- 2 high-volume institutions
Primary result
Remifentanil consumption
Mean difference
−0.04 mcg/kg/min
95% CI −0.06 to −0.02
P < 0.0001
ANB at the onset vs Control
mean difference −0.04 mcg/kg/min (95% CI −0.06 to −0.02); P < 0.0001
As reported in the abstract
Secondary outcomes
Aldrete scale scores in recovery room
- No differences between the 2 groups
Intraoperative mean HR and mean arterial pressure (MAP)
- Significantly less during surgery in the ANB at the onset group
Safety
- No complications related to the ANB occurred
Original publication
Impact on Anesthetic Agent Consumption After Autonomic Neural Blockade as Part of a Combined Anesthesia Protocol: A Randomized Clinical Trial. Anesth Analg. Published 13 December 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →