Perioperative medicine & outcomes
Impact of a Personalized Intervention on Preoperative Anxiety and Determination of the Minimal Clinically Important Difference in Anxiety Levels: A Randomized Clinical Trial
Primary result · Anesthesia-related anxiety after randomisationResult — go to the resultTwo-way interaction F(5, 96.291) 7.449Authors' conclusion
A personalized and information-based intervention can reduce anesthesia- and surgery-related anxiety to a statistically significant and clinically relevant degree.
Study context
- Population
- Adults awaiting elective surgery under GA
- Participants
- 122 adults
- Comparison
- Intervention vs Control
- Primary endpoint
- Anesthesia-related anxiety (personalized and information-based intervention hypothesised to reduce it)
Methodological detailssingle-centre, prospective, 1:1 randomisation
- Single-centre
- Prospective
- 1:1 randomisation
Primary result
Anesthesia-related anxiety after randomisation
Two-way interaction F(5, 96.291)
7.449
P < 0.001
As reported in the abstract
Further findings
| Outcome | Two-way interaction F(5, 112.486) | P value |
|---|---|---|
| Surgery-related anxiety after randomisation | 5.466 | P < 0.001 |
Surgery-related anxiety after randomisation
- Reduced surgery-related anxiety in the intervention vs control group
Minimal clinically important difference in APAIS anxiety scores
Points
- Anesthesia-related anxiety
- 1.03
- Surgery-related anxiety
- 1.13
Original publication
Impact of a Personalized Intervention on Preoperative Anxiety and Determination of the Minimal Clinically Important Difference in Anxiety Levels: A Randomized Clinical Trial. Anesthesiology. Published 26 December 2024. doi:10.
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