Perioperative medicine & outcomes

Impact of spinal versus general anaesthesia on perioperative obstructive sleep apnoea severity in patients undergoing hip arthroplasty: a post hoc analysis of two randomised controlled trials

Br J AnaesthPublished Post hoc analysis of two randomised controlled trials

Authors' conclusion

Use of spinal anaesthesia compared with general anaesthesia was not associated with a reduction in postoperative sleep apnoea severity, which was worse on the third postoperative night.

Study context

Population
Patients undergoing total hip arthroplasty2 RCTs pooled
Participants
96 patients
Comparison
Spinal vs general anaesthesia
Primary endpoint
Supine apnoea-hypopnea index on the first postoperative night and its evolution up to the third postoperative night
Follow-up
First postoperative night
Methodological detailspooled data, no preliminary power analysis
  • Pooled data
  • No preliminary power analysis

Primary result

As reported in the abstract

Supine apnoea-hypopnoea index

P = 0.82

Secondary outcomes

Supine apnoea-hypopnoea index · third postoperative night

P = 0.91

Secondary outcomes incl. oxygen desaturation index (first and third postoperative nights)

Similar in the two groups

Original publication

Impact of spinal versus general anaesthesia on perioperative obstructive sleep apnoea severity in patients undergoing hip arthroplasty: a post hoc analysis of two randomised controlled trials. Br J Anaesth. Published 10 June 2024. doi:10.1016/j.bja.2024.04.051

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