Cardiac arrest & resuscitation

Improving vasopressor use in cardiac arrest

Crit CarePublished Narrative review

Study context

Population
Patients in cardiac arrest
Comparison
Vasopressors and drug administration routes in cardiac arrest
Outcome
Effect of vasopressors in cardiac arrest (ROSC, 30-day survival, survival with favourable neurological outcome)

Main finding

As reported in the abstract

  • Adrenaline (1 mg) highly effective at achieving ROSC (NNT 4)
  • Adrenaline less effective on survival to 30 days (NNT 111)
  • Uncertain effects of adrenaline on survival with a favourable neurological outcome
  • Vasopressin (alternative to or in addition to adrenaline) and high-dose adrenaline: no evidence of improved long-term outcomes in RCTs
  • Narrative review

Original publication

Improving vasopressor use in cardiac arrest. Crit Care. Published 2 March 2023. doi:10.1186/s13054-023-04301-3

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