Cardiothoracic & vascular anesthesia
Increased Incidence of Thrombosis in Patients at Risk of Heparin-Induced Thrombocytopenia Receiving Epoprostenol for Cardiac Surgery
Authors' conclusion
The rate of thrombosis in our review was considerably higher than the published data on the use of prostacyclin analogues with heparin in patients with HIT, suggesting that this strategy may not be as effective for preventing thrombosis as previously thought.
Study context
- Population
- Adults with confirmed or suspected heparin-induced thrombocytopenia (HIT) undergoing cardiac surgery, tertiary referral centre, 2014–2024
- Participants
- 16 adults
- Outcome
- Postoperative thromboembolic event, HIT antibody- and serotonin release assay-positive patients
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Positive serotonin release assay
66.7%
4 events
Observational data: associations, not effects.
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Increased Incidence of Thrombosis in Patients at Risk of Heparin-Induced Thrombocytopenia Receiving Epoprostenol for Cardiac Surgery. J Cardiothorac Vasc Anesth. Published 15 November 2025. doi:10.
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