Respiratory failure & ventilation
Increased national critical care demands were associated with a higher mortality of intubated COVID-19 patients in Japan: a retrospective observational study
Authors' conclusion
The national critical care demands were independently associated with the mortality of COVID-19 patients requiring mechanical ventilation. This effect was more pronounced in hospitals with higher baseline risk.
Study context
- Population
- Mechanically ventilated COVID-19 patients in a Japanese national database, February 6, 2020–May 16, 2023
- Participants
- 8,327 participants · 264 centers
- Exposure
- Association of national critical care demands and overall medical demands with mortality
- Outcome
- Mortality
Methodological detailsnational database, multicentre, multivariable logistic regression, generalized linear mixed effect model
- National database
- Multicentre
- Multivariable logistic regression
- Generalized linear mixed effect model
Main finding
As reported in the abstract
Critical care demands (total number of critically ill COVID-19 patients) independently associated with mortality, OR
1.11
95% CI 1.07–1.16p < 0.001
Overall mortality rate
24%
1990/8327
Observational data: associations, not effects.
Further findings
Variation in effect of critical care demands across hospitals vs baseline risk
- Effect of critical care demands on mortality more pronounced in hospitals with higher baseline risk
- r = 0.67
Original publication
Increased national critical care demands were associated with a higher mortality of intubated COVID-19 patients in Japan: a retrospective observational study. J Intensive Care. Published 5 November 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →