Cardiothoracic & vascular anesthesia
Increasing obesity is associated with lower postoperative bleeding in coronary bypass patients
Authors' conclusion
Patients with high BMI may carry protection against postoperative bleeding after cardiac surgery, probably secondary to an inherent hypercoagulable state, whereas underweight patients carry a higher risk of bleeding and worse outcomes.
Study context
- Population
- CABG patients undergoing surgery 2007 to 2020, Western Denmark Heart Registry
- Participants
- 12,330 patients
- Exposure
- Body mass index (BMI) categories
- Outcome
- Postoperative bleeding (postoperative drainage) and transfusion requirements
Methodological detailsmulticentre, three university hospitals
- Multicentre
- Three university hospitals
Main finding
As reported in the abstract
Postoperative drainage
P < 0.0001
Observational data: associations, not effects.
Further findings
RBC transfusion
Average RBC transfusion BMI <18.5 451 mL/m² · BMI ≥40 84 mL/m²
- RBC transfusion: abstract labels this group BMI >40
Reexploration for bleeding; perioperative hemostatics, inotropes, vasoconstrictors
- Obese groups less often reexplored for bleeding and fewer received perioperative hemostatics, inotropes and vasoconstrictors
Mortality (30-day, 6-month, 1-year)
- Crude 30-day and 6-month mortality increased with lower BMI; 1-year mortality V-shaped
- BMI had no independent impact on mortality in logistic regression
Original publication
Increasing obesity is associated with lower postoperative bleeding in coronary bypass patients. J Cardiothorac Vasc Anesth. Published 17 March 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →