Preoperative Alcohol Use, Postoperative Pain, and Opioid Use After Coronary Artery Bypass Surgery
Authors' conclusion
There is no apparent association among mild-to-moderate preoperative alcohol consumption and early postoperative pain and opioid use in patients who underwent CABG.
Study context
- Population
- Patients having isolated coronary artery bypass grafting (CABG) at a single academic medical center
- Participants
- 1,338 patients
- Exposure
- Preoperative alcohol use categories vs no weekly alcohol use
- No alcoholn = 764reference
- ≤1 drinkn = 294
- 2-to-7 drinksn = 170
- 8 or more drinksn = 110
- Outcome
- Mean pain score and morphine milligram equivalent (MME) consumption
- Follow-up
- POD 0
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Mean pain score
No alcohol
5.3
mean · ± 2.2
≤1 drink
5.2
mean · ± 2.1
2-to-7 drinks
5.3
mean · ± 2.3
8 or more drinks
5.4
mean · ± 1.9
P = 0.66
Observational data: associations, not effects.
Further findings
MME use (co-primary) · POD 0 · no significant difference
P = 0.14
Original publication
Preoperative Alcohol Use, Postoperative Pain, and Opioid Use After Coronary Artery Bypass Surgery. J Cardiothorac Vasc Anesth. Published 22 January 2024. doi:10.
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