Sepsis & infection

Infection-related hospital readmissions after surviving sepsis: A retrospective population level study of adult sepsis survivors in Australia

J Crit CarePublished Retrospective cohort study

An erratum to this article was published (J Crit Care, Oct 2026 ↗)

Authors' conclusion

Early and unexpected hospital readmissions are common in Australian sepsis survivors with almost 15% returning to hospital through the ED within 30 days, a third of which were for another sepsis or infection event.

Study context

Population
Adult sepsis survivors with an index hospital admission between Jan 1, 2015, and Jan 31, 2021, in any hospital in New South Wales, Australia
Participants
125,370 survivors
Outcome
All-cause, sepsis or infection readmission through the ED
Follow-up
30 days
Methodological detailspopulation level, multivariable logistic regression
  • Population level
  • Multivariable logistic regression

Main finding

As reported in the abstract

All-cause readmission through the ED

All-cause readmission through the emergency department (ED), n (%)

18,731

14.9%

Readmissions with a sepsis diagnosis, n (%)

1910

10.2%

Readmissions with an infection diagnosis, n (%)

4790

25.6%

Observational data: associations, not effects.

Secondary outcomes

Risk factors for sepsis or infection-related readmission within 30 days

Higher risk: male sex, not being married, and chronic pulmonary disease, liver disease, diabetes, renal disease, malignancies, or malignant tumour comorbidities
Lower risk: aged 16-44 years (vs >85 years), inner regional areas (vs major cities), least socioeconomically disadvantaged area (vs most), and MI, cerebrovascular disease, or peptic ulcer disease comorbidities

Original publication

Infection-related hospital readmissions after surviving sepsis: A retrospective population level study of adult sepsis survivors in Australia. J Crit Care. Published 23 January 2026. doi:10.1016/j.jcrc.2026.155443

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