Neuroanesthesia & neurocritical care
Influence of alcohol on in-hospital survival rate among patients with traumatic brain injury: a nationwide cohort study
Main finding · In-hospital survivalResult — go to the resultRisk difference 5.2% 95% CI 4.7–5.7Authors' conclusion
In this nationwide study, preinjury alcohol consumption was associated with higher in-hospital survival among patients with TBI.
Study context
- Population
- Patients with head injuries and documented pre-injury alcohol consumption status, Japan Trauma Data Bank (≈290 hospitals), 2004–2018
- Participants
- 83,789 patients
- Exposure
- Pre-injury alcohol consumption vs no alcohol
- Alcoholn = 15,752
- Non-alcoholn = 68,037reference
- Outcome
- In-hospital survival
Methodological detailsnationwide registry, propensity score methods (inverse probability weighting (IPTW) and overlap weighting), generalized estimating equation
- Nationwide registry
- Propensity score methods (IPTW and overlap weighting)
- Generalized estimating equation
Main finding
As reported in the abstract
Risk difference
5.2%
95% CI 4.7–5.7
By group
Alcohol vs Non-alcohol
risk difference 5.2% (95% CI 4.7–5.7)
Observational data: associations, not effects.
Further findings
| Outcome | Alcohol | Non-alcohol | Risk difference in in-hospital survival (95% CI) | |
|---|---|---|---|---|
| In-hospital survival, IPTW-adjustedInverse probability weighting | 92.0% | 86.1% | 6.2% (5.9–6.2) | |
| In-hospital survival, overlap weighting-adjustedOverlap weighting | 91.7% | 85.4% | 7.0% (6.1–7.8) | |
| −50510Difference (linear scale) |
| Outcome | OR for survival (higher = more survival) (95% CI) | P value | |
|---|---|---|---|
| Survival, multivariate logistic regressionMultivariate logistic regression model | 1.58 (1.47–1.70) | P < 0.001 | |
| 0.512OR for survival (higher = more survival) (log scale) |
- Survival, multivariate logistic regression: preinjury alcohol consumption associated with higher survival
Original publication
Influence of alcohol on in-hospital survival rate among patients with traumatic brain injury: a nationwide cohort study. Crit Care. Published 24 March 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →