Influence of contrast medium on long-term renal function and outcomes in patients with septic acute kidney injury: A propensity-matched cohort study
Authors' conclusion
The administration of intravenous contrast medium was not associated with long-term mortality, deterioration of renal function, or dialysis in patients with septic AKI.
Study context
- Population
- Adults with septic acute kidney injury (AKI) admitted with septic shock
- Participants
- 609 adults · 133 matched pairs
- Exposure
- Contrast CT vs non-contrast CT
- Contrast CTn = 220
- Non-contrast CTn = 389reference
- Outcome
- Rates of 90-day mortality and dialysis within 90 days
- Follow-up
- 90 days
Methodological detailspropensity-matched
- Propensity-matched
Main finding
As reported in the abstract
90-day mortality; dialysis within 90 days
90-day mortality; dialysis within 90 days
Dialysis within 90 days
P = 0.655
- Contrast CT vs Non-contrast CT: P = 0.579 — 90-day mortality
Observational data: associations, not effects.
Secondary outcomes
Worsening AKI
P = 0.706
In-hospital mortality
P = 0.369
Maintenance of dialysis after 90 days
P > 0.99
Original publication
Influence of contrast medium on long-term renal function and outcomes in patients with septic acute kidney injury: A propensity-matched cohort study. J Crit Care. Published 20 August 2024. doi:10.
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