Cardiothoracic & vascular anesthesia

Influence of HeartMate 3™ on Bispectral Index™ monitor: a retrospective observational study

J Clin Monit ComputPublished Retrospective observational study

Authors' conclusion

HeartMate 3 significantly elevates EMG.

Study context

Population
Patients undergoing HeartMate 3 or II implantation, April 2008–December 2023
Participants
33 vs 43
Exposure
Pre-LVAD vs post-LVAD period EMG and BIS, HeartMate 3 vs HeartMate II
  • HeartMate 3n = 33
  • HeartMate IIn = 43reference
Outcome
Patient-wise median EMG and BIS, pre-LVAD (start of surgery to CPB initiation) vs post-LVAD (end of CPB to end of surgery)
Methodological detailssingle institutional database
  • Single institutional database

Main finding

As reported in the abstract

EMG, HeartMate 3

P < 0.001

Observational data: associations, not effects.

Further findings

OutcomeValuesP value
BIS, HeartMate 3HeartMate 3 post-LVAD vs HeartMate 3 pre-LVAD · no significant changeHeartMate 3 pre-LVAD mean 44.5 (SD 8.1) · HeartMate 3 post-LVAD mean 45.5 (SD 7.1)P = 0.35
EMG, HeartMate IIHeartMate II post-LVAD vs HeartMate II pre-LVAD · no significant changeHeartMate II pre-LVAD mean 26.1 (SD 1.2) dB · HeartMate II post-LVAD mean 27.1 (SD 4.1) dBP = 0.16
BIS, HeartMate IIHeartMate II post-LVAD vs HeartMate II pre-LVAD · no significant changeHeartMate II pre-LVAD mean 45.1 (SD 9.2) · HeartMate II post-LVAD mean 43.0 (SD 8.1)P = 0.071

Original publication

Influence of HeartMate 3™ on Bispectral Index™ monitor: a retrospective observational study. J Clin Monit Comput. Published 6 March 2025. doi:10.1007/s10877-025-01272-4

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