Cardiothoracic & vascular anesthesia
Influence of HeartMate 3™ on Bispectral Index™ monitor: a retrospective observational study
Authors' conclusion
HeartMate 3 significantly elevates EMG.
Study context
- Population
- Patients undergoing HeartMate 3 or II implantation, April 2008–December 2023
- Participants
- 33 vs 43
- Exposure
- Pre-LVAD vs post-LVAD period EMG and BIS, HeartMate 3 vs HeartMate II
- HeartMate 3n = 33
- HeartMate IIn = 43reference
- Outcome
- Patient-wise median EMG and BIS, pre-LVAD (start of surgery to CPB initiation) vs post-LVAD (end of CPB to end of surgery)
Methodological detailssingle institutional database
- Single institutional database
Main finding
As reported in the abstract
EMG, HeartMate 3
P < 0.001
Observational data: associations, not effects.
Further findings
| Outcome | Values | P value |
|---|---|---|
| BIS, HeartMate 3HeartMate 3 post-LVAD vs HeartMate 3 pre-LVAD · no significant change | HeartMate 3 pre-LVAD mean 44.5 (SD 8.1) · HeartMate 3 post-LVAD mean 45.5 (SD 7.1) | P = 0.35 |
| EMG, HeartMate IIHeartMate II post-LVAD vs HeartMate II pre-LVAD · no significant change | HeartMate II pre-LVAD mean 26.1 (SD 1.2) dB · HeartMate II post-LVAD mean 27.1 (SD 4.1) dB | P = 0.16 |
| BIS, HeartMate IIHeartMate II post-LVAD vs HeartMate II pre-LVAD · no significant change | HeartMate II pre-LVAD mean 45.1 (SD 9.2) · HeartMate II post-LVAD mean 43.0 (SD 8.1) | P = 0.071 |
Original publication
Influence of HeartMate 3™ on Bispectral Index™ monitor: a retrospective observational study. J Clin Monit Comput. Published 6 March 2025. doi:10. 1007/ s10877-025-01272-4
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