Respiratory failure & ventilation
Inspiratory effort estimated by airway occlusion pressure in the presence of intrinsic positive end-expiratory pressure
Authors' conclusion
this proof-of-concept study shows that ΔPocc may underestimate inspiratory effort in case of PEEPi. When a plateau airway pressure can be observed in the end of ΔPocc, it seems possible to estimate PEEPi noninvasively.
Study context
- Population
- Patients with various degrees of PEEPi undergoing PEEP titration during pressure support ventilation (PSV) with esophageal pressure
- Outcome
- Estimation of inspiratory effort by ΔPocc in the presence of PEEPi
Methodological detailsproof-of-concept study, PEEP titration during PSV with esophageal pressure, linear mixed-effects models
- Proof-of-concept study
- PEEP titration during PSV with esophageal pressure
- Linear mixed-effects models
Main finding
As reported in the abstract
PEEPi, mean (± SD), PEEP 2 cmH2O
4.7 (± 5.0) cmH2O
PEEPi, mean (± SD), PEEP 14 cmH2O
1.2 (± 0.7) cmH2O
Observational data: associations, not effects.
Original publication
Inspiratory effort estimated by airway occlusion pressure in the presence of intrinsic positive end-expiratory pressure. Crit Care. Published 22 April 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →