Neuroanesthesia & neurocritical care
Institutional Variability in Brain-Dead Organ Donation Processes and Practices: A Multicenter Cohort Study
Authors' conclusion
Highly active hospitals demonstrated more intensive donor management practices, longer timeframes for key donation steps, and greater multidisciplinary engagement.
Study context
- Population
- Brain-dead organ donors with at least one organ procured and transplanted, 16 tertiary emergency and critical care centres in Japan, July 17, 2010–December 31, 2023
- Participants
- 204 donors · 16 centres
- Exposure
- Highly active vs moderately active brain-dead organ donation hospitals
- Outcome
- Institutional donation practices: donor management strategies, use of vasopressors and corticosteroids, time intervals in the donation process, frequency of multidisciplinary team meetings
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
- Highly active
- Corticosteroid use 58.3% vs. 38.0%; P = 0.004
- Highly active
- Time to family consent, median 8 vs. 5 d; P < 0.001
- Highly active
- Time to organ procurement, median 12 vs. 9 d; P = 0.006
- Highly active
- Multidisciplinary meetings during donor management, median 2 vs. 0; P < 0.001
Observational data: associations, not effects.
Original publication
Institutional Variability in Brain-Dead Organ Donation Processes and Practices: A Multicenter Cohort Study. Crit Care Med. Published 26 March 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →