Neuroanaesthesia & neurocritical care
Sequence and timing of organ donation discussions in brain-dead donors: a subanalysis of the J-RESPECT study
Primary result · Presentation sequence and associated factorsResult — go to the resultAdjusted odds ratio 1.03 95% CI 1.00–1.07Authors' conclusion
Substantial inter-institutional variability exists in the sequence and timing of organ donation discussions in Japan.
Study context
- Population
- Adult brain-dead donors from 16 institutions in Japan, 2010–2023
- Participants
- 190 donors · 16 institutions
- Comparison
- Brain death-first vs Option-first
- Brain death-firstn = 76reference
- Option-firstn = 114
- Primary endpoint
- Sequence of organ donation option presentation relative to clinical determination of a brain death-compatible state, and factors associated with it
Methodological detailsmulticentre retrospective cohort study, mixed-effects regression with random intercepts for institution
- Multicentre retrospective cohort study
- Mixed-effects regression with random intercepts for institution
Primary result
Presentation sequence and associated factors
Adjusted odds ratio
1.03
95% CI 1.00–1.07
Events by treatment group
Age (per year)
aOR 1.03 (95% CI 1.00–1.07)
Per year, as printed
As reported in the abstract
- Between-institution variability (intraclass correlation coefficient)
- 0.32
Further findings
Interval from admission to option presentation
P < 0.001
Original publication
Sequence and timing of organ donation discussions in brain-dead donors: a subanalysis of the J-RESPECT study. J Intensive Care. Published 28 July 2026. doi:10.
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