Pediatric anesthesia & critical care
Practice Variation in Intraoperative Management of Pediatric Organ Donation After Brain Death: A Retrospective Observational Multicenter Perioperative Outcomes Group Study
Main finding · Intraoperative practice variationResult — go to the resultOdds ratio 0.319 95% CI 0.116–0.745Authors' conclusion
This study found substantial practice variation across MPOG centers grouped based on case volume frequency for organ recovery procedures in pediatric donation after brain death.
Study context
- Population
- Pediatric (age < 18 years) brain-dead organ donors undergoing organ recovery at 24 Multicenter Perioperative Outcomes Group (MPOG) centres in the US, 2014–2020
- Participants
- 231 participants · 24 centres
- Exposure
- Higher-Volume vs Lower-Volume centres
- Outcome
- Practice patterns for intraoperative management during organ recovery
Methodological detailsmulticentre, no adjustment for multiple comparisons
- Multicentre
- No adjustment for multiple comparisons
Main finding
Intraoperative practice variation
Odds ratio
0.319
95% CI 0.116–0.745
P = 0.014
By group
Lower-Volume vs Higher-Volume
OR 0.319 (95% CI 0.116–0.745); P = 0.014
As reported in the abstract
Observational data: associations, not effects.
Original publication
Practice Variation in Intraoperative Management of Pediatric Organ Donation After Brain Death: A Retrospective Observational Multicenter Perioperative Outcomes Group Study. Paediatr Anaesth. Published 1 October 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →