Hemodynamics, fluids & transfusion
Integrating Right Ventricular Pressure Waveform Analysis With Two-Point Volume Measurement for Quantification of Systolic and Diastolic Function: Experimental Validation and Clinical Application
Authors' conclusion
Study results supported the possibility of integrating automated RV pressure analysis with RV volume measured by 3D echocardiography to create a comprehensive assessment of RV systolic and diastolic function at the bedside.
Study context
- Population
- Archived data from anesthetized swine and awake patients undergoing clinically-indicated right-heart catheterization
- Exposure
- Single-beat measures of right ventricular (RV) contractility and diastolic capacitance vs multi-beat, preload-variant reference standards
- Outcome
- Single-beat RV end-systolic elastance and V15 vs multi-beat reference standards (correlation, Bland-Altman, 4-quadrant concordance)
Methodological detailsexperimental validation, clinical application, University laboratory
- Experimental validation
- Clinical application
- University laboratory
Main finding
As reported in the abstract
- Methods not directly interchangeable with reference standards, but sufficiently robust to suggest potential clinical utility
Observational data: associations, not effects.
Further findings
Clinical application: response to inhaled nitric oxide during diagnostic right-heart catheterization
- Enhanced assessment of the response to inhaled nitric oxide
Original publication
Integrating Right Ventricular Pressure Waveform Analysis With Two-Point Volume Measurement for Quantification of Systolic and Diastolic Function: Experimental Validation and Clinical Application. J Cardiothorac Vasc Anesth. Published 13 June 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →