Cardiothoracic & vascular anesthesia
Intraoperative ventilation risk factors for postoperative pulmonary complications in patients undergoing elective neoplastic esophagectomy: a retrospective cohort study
Authors' conclusion
Pplat, RR, and DP were associated with PPCs in both ventilation phases. During TLV, duration increased and PEEP decreased PPC risk, whereas during OLV, VTe and MP were associated with PPCs.
Study context
- Population
- Patients undergoing elective esophagectomy with combined abdominal and thoracic approaches
- Participants
- 454 patients
- Outcome
- Occurrence of PPCs
- Follow-up
- Within seven postoperative days
Methodological detailssingle-center
- Single-center
Main finding
As reported in the abstract
PPCs
Postoperative pulmonary complications (PPCs) occurred (194 patients)
42.7%
Respiratory rate: OR up to
1.62
Positive end-expiratory pressure (PEEP), two-lung ventilation (TLV) (protective): OR
0.73
Model discrimination (acceptable): AUC
0.70-0.76
Observational data: associations, not effects.
Original publication
Intraoperative ventilation risk factors for postoperative pulmonary complications in patients undergoing elective neoplastic esophagectomy: a retrospective cohort study. Anaesth Crit Care Pain Med. Published 17 February 2026. doi:10.
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