Respiratory failure & ventilation

Intraoperative ventilation settings in Germany: an observational multicentre cross-sectional study

Can J AnaesthPublished pragmatic prospective observational national cross-sectional assessment

Authors' conclusion

This large-scale clinical study of intraoperative ventilation settings in Germany found that most anesthesiologists already followed current recommendations. Therefore, for the entire cohort, no major improvements were observed. The educational intervention might improve ventilation settings in anesthesiology departments whose baseline practice deviates strongly from current recommendations.

Study context

Population
Anesthesiology departments and operating rooms in Germany; intraoperative ventilation settingsoperating rooms in the first (preintervention) assessment, 2,106 in the second (postintervention) assessment, over 240 of 1,148 anesthesiology departments participated (21%), 96% response rate · first (preintervention) assessment, operating rooms 2,198 · second (postintervention) assessment, operating rooms 2,106
Participants
2,198 participants
Exposure
First vs second assessment
  • First assessmentn = 2,198
  • Second assessmentn = 2,106
Outcome
Patient-centred primary endpoint: tidal volume (VT)·kg-1 ideal body weight (IBW)
Methodological detailsmulticentre, followed by an educational intervention and follow-up assessment, post hoc analysis by quintiles of baseline VT and fresh gas flow (FGF)
  • Multicentre
  • Followed by an educational intervention and follow-up assessment
  • Post hoc analysis by quintiles of baseline VT and FGF

Main finding

As reported in the abstract

Observational data: associations, not effects.

Further findings

Environment-centred primary endpoint: FGF in inhalational anesthesia · environment-centred primary endpoint

Effect of the intervention (exploratory multilevel regression analysis)

Exploratory multilevel regression analysis did not show an effect of the intervention

Departments with baseline ventilation settings in the highest quintile (post hoc)

The intervention was associated with improvements in both VT and FGF
  • Post hoc analysis

Original publication

Intraoperative ventilation settings in Germany: an observational multicentre cross-sectional study. Can J Anaesth. Published 7 October 2026. doi:10.1007/s12630-026-03172-w

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