Organ support & nutrition

Kidney recovery after iodinated contrast administration in patients with acute kidney injury receiving renal replacement therapy

J Crit CarePublished Retrospective cohort study

Main finding · RRT dependence at hospital dischargeResult — go to the resultOdds ratio 1.73 95 % CI 1.13–2.53

Authors' conclusion

The receipt of contrast in patients with AKI receiving RRT was associated with an increased risk of RRT dependence at hospital discharge.

Study context

Population
Patients with Acute Kidney Injury (AKI) receiving Renal Replacement Therapy (RRT) at St Michael's Hospital, Toronto, Canada, January 2007 to December 2022of 1597 receiving RRT
Participants
754 patients
Exposure
Iodinated contrast vs no contrast during RRT
  • Contrastn = 185
Outcome
RRT dependence at hospital discharge
Follow-up
Hospital discharge
Methodological detailspropensity score weighting, single-centre
  • Propensity score weighting
  • Single-centre

Main finding

As reported in the abstract

Odds ratio

1.73

95 % CI 1.13–2.53

Contrast vs No contrast
OR 1.73 (95 % CI 1.13–2.53)

Observational data: associations, not effects.

Original publication

Kidney recovery after iodinated contrast administration in patients with acute kidney injury receiving renal replacement therapy. J Crit Care. Published 30 January 2025. doi:10.1016/j.jcrc.2025.155015

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