Cardiac arrest & resuscitation

Lactate and pH as Predictors of In-Hospital Mortality in Extracorporeal Cardiopulmonary Resuscitation: A Single-Center Retrospective Study

J Cardiothorac Vasc AnesthPublished Retrospective cohort study

Study context

Population
Adults undergoing extracorporeal cardiopulmonary resuscitation (ECPR) at a single quaternary academic center, September 2011–April 2025
Participants
484 adults
Exposure
Non-survivors vs Survivors
Outcome
Precannulation lactate and pH vs in-hospital mortality
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

Non-survivors

9.3

median

Survivors

7.3

median

Multivariable logistic regression
Estimate (95% CI)
Lactate
OR 1.13 per mmol/L(1.05–1.22)
pH
OR 0.61 per 0.1 unit(0.47–0.76)

Each row per its own increment, as printed

In-hospital mortality
62.4%
Optimal cut point for lactate (Youden index)
10.85 mmol/L
Optimal cut point for pH (Youden index)
7.2

Observational data: associations, not effects.

Further findings

Overall precannulation lactate and pH

Median lactate, mmol/L (IQR 4.1-12.3)
8.7
Median pH (IQR 7.09-7.34)
7.23

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Lactate and pH as Predictors of In-Hospital Mortality in Extracorporeal Cardiopulmonary Resuscitation: A Single-Center Retrospective Study. J Cardiothorac Vasc Anesth. Published 3 September 2026. doi:10.1053/j.jvca.2026.08.166

Composed by AI from the published abstract and checked against it. How Briefs are made →

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