Cardiac arrest & resuscitation
Regional Cerebral Oxygen Saturation to Predict Favorable Outcome in Extracorporeal Cardiopulmonary Resuscitation: A Systematic Review and Meta-Analysis
Pooled result · MortalityResult — go to the resultRisk difference −0.30 95% CI −0.47 to −0.14Authors' conclusion
A low rSO2 before starting ECPR could be a predictor of mortality and survival with poor neurologic outcomes.
Study context
- Population
- Adult in-hospital and out-of-hospital cardiac arrest patients receiving extracorporeal cardiopulmonary resuscitation (ECPR)
- Participants
- 245 participants · 3 observational studies
- Comparison
- High vs low precannulation rSO2
- High rSO2n = 151
- Low rSO2n = 94reference
- Outcome
- Mortality
Methodological detailssubgroup analysis
- Subgroup analysis
Pooled result
As reported in the abstract
Risk difference
−0.30
95% CI −0.47 to −0.14
Events by group
High rSO2 vs Low rSO2
risk difference −0.30 (95% CI −0.47 to −0.14)
Further pooled results
Mortality, OHCA (subgroup) · estimate printed without sign
RD 0.30 (−0.48 to −0.12)
| Outcome | High rSO2 | Low rSO2 | RD (95% CI) | |
|---|---|---|---|---|
| Good neurologic outcome | 27.8% | 2.12% | 0.22 (0.13–0.31) | |
| Good neurologic outcome, OHCA (subgroup) | 27.3% | 2.25% | 0.21 (0.11–0.30) | |
| −0.200.20.4Difference (linear scale) |
Original publication
Regional Cerebral Oxygen Saturation to Predict Favorable Outcome in Extracorporeal Cardiopulmonary Resuscitation: A Systematic Review and Meta-Analysis. J Cardiothorac Vasc Anesth. Published 9 January 2023. doi:10.
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