Cardiac arrest & resuscitation
Left ventricular energetics in patients receiving veno-arterial extracorporeal membrane oxygenation for extracorporeal cardiopulmonary resuscitation
Authors' conclusion
High VA-ECMO flow significantly reduced LVEDP, LVEDV, and LVSW compared to low VA-ECMO flow.
Study context
- Population
- Patients who underwent extracorporeal cardiopulmonary resuscitation (ECPR) on veno-arterial extracorporeal membrane oxygenation (VA-ECMO) and achieved ROSC; studied 3.0 (2.0, 4.0) days after cannulationECPR with ROSC
- Participants
- 15 patients
- Comparison
- Highest vs lowest VA-ECMO flow
- Outcome
- Left ventricular (LV) haemodynamics (LVEDV, LVEDP, LVSW) at highest vs lowest VA-ECMO flow
- Follow-up
- 3.0 days after cannulation (median)
Methodological detailspaired comparisons, invasive left heart catheterization and 3D echocardiography
- Paired comparisons
- Invasive left heart catheterization and 3D echocardiography
Main finding
As reported in the abstract
LVEDV (median) increased from highest (median 4.0 L/min) to lowest (median 2.0 L/min) VA-ECMO flow, p = 0.005
85 mL to 106 mL
Left ventricular end-diastolic pressure (LVEDP) (median) increased from highest to lowest VA-ECMO flow, p = 0.001
14 mmHg to 17 mmHg
LVSW (mean ± SD) increased from highest to lowest VA-ECMO flow, p = 0.01
2051 ± 1525 mL*mmHg to 2627 ± 1559
Further findings
Survival of index hospitalization
- Survived
- 6
- Died
- 9
Original publication
Left ventricular energetics in patients receiving veno-arterial extracorporeal membrane oxygenation for extracorporeal cardiopulmonary resuscitation. Resuscitation. Published 19 December 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →