Sepsis & infection

Linking Sepsis with chronic arterial hypertension, diabetes mellitus, and socioeconomic factors in the United States: A scoping review

J Crit CarePublished Scoping review

Authors' conclusion

The distribution of chronic arterial hypertension, diabetes mellitus, social risk factors associated with socioeconomic disadvantage, and sepsis incidence, are clustered in specific geographical areas and linked by endothelial dysfunction.

Study context

Population
English-language US articles, 1990–2022, on sepsis and socioeconomic disadvantage, chronic arterial hypertension and DMarticles included
Participants
139 articles
Outcome
Sepsis disparities and socioeconomic disadvantage
Methodological detailsSearched PubMed, Web of Science and Scopus; 2064 articles found
  • Searched PubMed, Web of Science and Scopus; 2064 articles found

Main finding

As reported in the abstract

  • Consistently higher sepsis incidence, mortality, readmissions and complications in neighborhoods with socioeconomic disadvantage and significant poverty
  • Chronic arterial hypertension and DM occur more frequently in the same geographic distribution as sepsis, suggesting a potential shared pathophysiology

Original publication

Linking Sepsis with chronic arterial hypertension, diabetes mellitus, and socioeconomic factors in the United States: A scoping review. J Crit Care. Published 7 May 2023. doi:10.1016/j.jcrc.2023.154324

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