Long-term characteristics and outcomes of septic critically ill patients with and without COVID-19
Authors' conclusion
In our cohort of septic critically ill patients, health-related quality of life and long-term survival were considerably reduced in patients with concomitant COVID-19. Furthermore, COVID-19 could be identified as an independent risk factor for higher long-term mortality in these patients.
Study context
- Population
- Septic (Sepsis-3) critically ill patients, 2020 to 2023
- Participants
- 301 vs 372
- Exposure
- Septic critically ill patients with vs without COVID-19
- COVID-19n = 301
- Without COVID-19n = 372reference
- Outcome
- Long-term mortality
- Follow-up
- 6-12 months after sepsis diagnosis
Methodological detailsregistry-based
- Registry-based
Main finding
As reported in the abstract
6-12 months
COVID-19 vs Without COVID-19Estimate (95 % CI)P value
Long-term mortality
HR 3.4(2.73–4.27)
P < 0.05Cox regression
adjusted HR 3.27(2.48–4.33)
P < 0.05Observational data: associations, not effects.
Further findings
| Outcome | COVID-19 | Without COVID-19 | P value |
|---|---|---|---|
| Health-related quality of life (EQ-5D-3 L Index)Spread kind not named in abstract | 0.56 (range 0.16–0.79) | 0.79 (range 0.69–0.99) | P < 0.05 |
Baseline characteristics · ICU admission
- COVID-19 patients significantly younger, lower Charlson Comorbidity Index, higher SOFA score at ICU admission
Original publication
Long-term characteristics and outcomes of septic critically ill patients with and without COVID-19. J Crit Care. Published 31 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →