Long term opioid use after burn injury: a retrospective cohort study
Main finding · Opioid use after dischargeResult — go to the resultIncidence rate ratio 1.43Authors' conclusion
Opioid use is high in those admitted with a burn injury or acute pancreatitis when compared with the general population, increasing further after hospital discharge.
Study context
- Population
- Adults admitted with a burn injury from 2009 to 2019, with matched comparison cohortsmatched cohorts
- Participants
- 7,147 / 6,810 / 28,184
- Exposure
- Burn injury vs acute pancreatitis vs general population
- Burnn = 7,147
- Pancreatitisn = 6,810
- General populationn = 28,184reference
- Outcome
- Post-discharge opioid use
Methodological detailsmatched comparison cohorts, multivariable negative binomial regression
- Matched comparison cohorts
- Multivariable negative binomial regression
Main finding
Opioid use after discharge
Incidence rate ratio
1.43
By group
As reported in the abstract
Observational data: associations, not effects.
Further findings
Pre-admission opioid use
Factors associated with increased opioid prescriptions after discharge
- Female sex, lower socioeconomic status, ICU admission, pre-injury opioid use and history of excess alcohol use associated with increased opioid prescriptions
Original publication
Long term opioid use after burn injury: a retrospective cohort study. Br J Anaesth. Published 11 January 2024. doi:10.
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