Cardiothoracic & vascular anesthesia

Long-term Outcome of Reexploration for Bleeding After Coronary Artery Bypass Grafting

J Cardiothorac Vasc AnesthPublished Retrospective cohort study

Authors' conclusion

Reexploration for bleeding was significantly associated with higher 30-day mortality but not with long-term mortality.

Study context

Population
All patients undergoing coronary artery bypass grafting (CABG), January 1998 to December 2019
Participants
21,346 patients
Exposure
Reexploration for bleeding vs no reexploration after CABG
  • Reexploredn = 576
Outcome
All-cause mortality up to end of follow-up (June 1, 2021)
Follow-up
Median 9.7 years (IQR 5.1-14.6)
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

Long-term all-cause mortality

Hazard ratio

1.029

P = 0.068

Long-term all-cause mortality

Hazard ratio

0.982

P = 0.813

multivariate Cox regression with ≥5 packed red blood cell (pRBC) as cut-off

Observational data: associations, not effects.

Secondary outcomes

30-day mortality

Blood product transfusion and long-term mortality

Blood product transfusion, HR
1.135
pRBC transfusion, HR
1.139
≥5 pRBCs, HR
1.249
  • All p < 0.001

Original publication

Long-term Outcome of Reexploration for Bleeding After Coronary Artery Bypass Grafting. J Cardiothorac Vasc Anesth. Published 10 June 2023. doi:10.1053/j.jvca.2023.06.008

Composed by AI from the published abstract and checked against it. How Briefs are made →

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