Cardiac arrest & resuscitation

Long‐Term Outcomes After Cardiac Arrest: Protocol for the Extended Follow‐Up Sub‐Study of the STEPCARE Trial

Acta Anaesthesiol ScandPublished Study protocol for an extended follow-up sub-study of the STEPCARE randomised controlled trial

Study context

Population
Out-of-hospital cardiac arrest (OHCA) survivors and one caregiver per survivor at selected STEPCARE sitesestimated sample size
Participants
600 survivors
Planned comparison
Different targets of sedation, temperature and mean arterial pressure (MAP) management
Primary endpoint
Survivors: cognitive function (Montreal Cognitive Assessment); caregivers: caregiver burden (Zarit Burden Interview)
Follow-up
6 and 12 months
Methodological detailsinternational, multicentre, randomisation stratified by site
  • International
  • Multicentre
  • Randomisation stratified by site

No results yet. This paper sets out the design of a trial; its results are to come.

Original publication

Long‐Term Outcomes After Cardiac Arrest: Protocol for the Extended Follow‐Up Sub‐Study of the STEPCARE Trial. Acta Anaesthesiol Scand. Published 26 August 2025. doi:10.1111/aas.70114

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