ICU sedation, delirium & recovery
Long‐term recovery in critically ill COVID ‐19 survivors: A prospective cohort study
Authors' conclusion
Survivors of critical COVID-19 showed improved functional outcome and physical HRQoL from 3 to 12 months post-ICU. A shorter duration of mechanical ventilation is associated with good functional outcome and good HRQoL, while older age is associated with good functional outcome.
Study context
- Population
- Critically ill COVID-19 survivors admitted to six ICUs in Sweden, May 2020–May 2021six ICUs
- Exposure
- Functional outcome and Health-Related Quality of Life (HRQoL) at 3 vs 12 months
- Outcome
- Changes in functional outcome and HRQoL
- Follow-up
- Between 3 and 12 months
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
Good functional outcome (Glasgow Outcome Scale Extended (GOSE) ≥7)
P < 0.001
Observational data: associations, not effects.
Secondary outcomes
Mean
| Outcome | 3 months | 12 months | P value |
|---|---|---|---|
| Physical HRQoL (PCS) | 40 | 44 | P < 0.001 |
| Mental HRQoL (MCS)Within normal range at 3 months, no change | 46 | 48 | P = 0.05 |
Factors associated with good outcomes at 12 months (multivariable logistic regression)
- Increasing age associated with good functional outcome
- Lower clinical frailty and absence of DM associated with good physical component summary (PCS)
- Shorter duration of mechanical ventilation associated with good outcome for all three measures
Original publication
Long‐term recovery in critically ill COVID ‐19 survivors: A prospective cohort study. Acta Anaesthesiol Scand. Published 14 November 2024. doi:10.
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