Cardiac arrest & resuscitation
The semi-quantitative cardiac arrest brain ischemia (CABI) score for magnetic resonance imaging predicts functional outcome after cardiac arrest
Authors' conclusion
A semi-quantitative approach to MRI evaluations after cardiac arrest may increase the prognostic accuracy compared to non-standardized routine assessment.
Study context
- Population
- Adults (≥ 18 years) admitted to ICU after cardiac arrest at four Swedish hospitals, 2014 to 2018, examined with magnetic resonance imaging (MRI)4 blinded raters
- Participants
- 90 adults
- Exposure
- CABI score vs Routine qualitative assessment
- Outcome
- Prognostic performance for poor functional outcome (Cerebral Performance Category 3-5)
- Follow-up
- 2-6 months post-arrest
Methodological detailsprognostic accuracy, blinded raters, MRI at median 5 days (IQR: 3.7-6.3), 85.6% (n = 77) had poor functional outcome
- Prognostic accuracy
- Blinded raters
- MRI at median 5 days (IQR: 3.7-6.3)
- 85.6% (n = 77) had poor functional outcome
Main finding
As reported in the abstract
Prediction of poor functional outcome
| Group | AUC | Sensitivity | Specificity |
|---|---|---|---|
| CABI score | 0.87-0.92 | 59.7-85.7% | 76.9-100% |
| Routine assessment | — not stated in the abstract | 61-76.6% | 84.6-100% |
AUC
CABI score0.87-0.92
Routine assessment— not stated in the abstract
Sensitivity
CABI score59.7-85.7%
Routine assessment61-76.6%
Specificity
CABI score76.9-100%
Routine assessment84.6-100%
— not stated in the abstract
- CABI score vs Routine assessment: P < 0.05
Observational data: associations, not effects.
Further findings
| Outcome | CABI score |
|---|---|
| Inter-rater reliability | ICC 0.67 (95% CI 0.58–0.75) |
- Inter-rater reliability: Routine assessment Fleiss κ 0.64 (95% CI 0.53–0.75)
Inter-rater reliability
- Moderate agreement for both
Original publication
The semi-quantitative cardiac arrest brain ischemia (CABI) score for magnetic resonance imaging predicts functional outcome after cardiac arrest. Crit Care. Published 20 August 2025. doi:10.
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