Respiratory failure & ventilation
Longitudinal changes of electrical impedance tomography-based best PEEP in obese patients undergoing laparoscopic surgery: A prospective physiological study
Main finding · PEEPEITResult — go to the resultMedian increase 3 cmH2OAuthors' conclusion
EIT-based best PEEP changes dynamically and non-homogeneously during laparoscopic surgery in class I/II obese patients.
Study context
- Population
- Patients with Class I/II obesity undergoing laparoscopic abdominal surgery
- Participants
- 31 patients
- Exposure
- Electrical Impedance Tomography (EIT)-based best PEEP at T1 vs T2 vs T3
- Outcome
- Best PEEP according to EIT (PEEPEIT): intersection between regional collapse and overdistention
Methodological detailsdecremental PEEP titration at 3 timepoints
- Decremental PEEP titration at 3 timepoints
Main finding
PEEPEIT
Median increase
3 cmH2O
P < 0.001
By group
As reported in the abstract
- Coefficient of increase variation
- 60.8%
Observational data: associations, not effects.
Further findings
Correlation of T2–T1 PEEPEIT difference with intrabdominal pressure
- No correlation (r = −0.03, p = 0.88)
Association of T2–T1 PEEPEIT difference with trunk inclination
- Significant association (r = 0.42, p = 0.018)
Original publication
Longitudinal changes of electrical impedance tomography-based best PEEP in obese patients undergoing laparoscopic surgery: A prospective physiological study. Anaesth Crit Care Pain Med. Published 13 June 2025. doi:10.
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