Hemodynamics, fluids & transfusion
Low-Volume Acute Normovolemic Hemodilution Does Not Reduce Allogeneic Red Blood Cell Transfusion in Cardiac Surgery in the Modern Era of Patient Blood Management: A Propensity Score-Matched Cohort Study
Main findingResult — go to the resultOdds ratio 0.72 95% CI 0.32–1.55Authors' conclusion
Low-volume ANH was not associated with a significant reduction in perioperative allogeneic RBC transfusion during cardiac surgery with CPB using low-priming-volume circuits.
Study context
- Population
- Patients undergoing elective cardiac surgery with cardiopulmonary bypass (CPB) using low-priming-volume circuits, single university hospital, January 2017–March 202249 acute normovolemic hemodilution (ANH) matched to 97 controls
- Participants
- 542 patients
- Exposure
- Low-volume ANH vs no ANH
- ANHn = 49
- Controln = 97reference
- Outcome
- Proportion of patients receiving perioperative red blood cell (RBC) transfusion
Methodological detailspropensity-score matched, single-centre
- Propensity-score matched
- Single-centre
Main finding
As reported in the abstract
Odds ratio
0.72
95% CI 0.32–1.55
P = 0.42
By group
ANH vs Control
OR 0.72 (95% CI 0.32–1.55); P = 0.42
Observational data: associations, not effects.
Further findings
- ANH volume
- 450 · median · IQR 400–800 · mL
Original publication
Low-Volume Acute Normovolemic Hemodilution Does Not Reduce Allogeneic Red Blood Cell Transfusion in Cardiac Surgery in the Modern Era of Patient Blood Management: A Propensity Score-Matched Cohort Study. J Cardiothorac Vasc Anesth. Published 4 November 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →