ICU sedation, delirium & recovery
Lower mean phosphate independently predicts mortality in critically ill patients: Results from a prospective cohort study
Authors' conclusion
Hypophosphatemia is frequent in the ICU, and was associated with unfavorable outcomes.
Study context
- Population
- Adult intensive care unit (ICU) patients (> 18 years) with ICU LOS of at least 24 h
- Participants
- 317 patients
- Exposure
- Hypophosphatemia vs Control
- Hypophosphatemian = 111
- Outcome
- ICU and in-hospital mortality (prognostic value of lower mean phosphate)
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
ICU and in-hospital mortality, independent predictors (multivariate)
Relative risk (95% CI)P value
Lower mean phosphate
0.02(0.001–0.09)
P = 0.044Higher APACHE II
1.1(1.01–1.2)
P = 0.045Observational data: associations, not effects.
Further findings
- Prevalence of hypophosphatemia
- 35% · 111
Severity scores and mortality
- Admission APACHE II, SOFA (ICU days 1, 3, 7) and ICU and in-hospital mortality greater in the hypophosphatemia group than control
Original publication
Lower mean phosphate independently predicts mortality in critically ill patients: Results from a prospective cohort study. J Crit Care. Published 2 February 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →