Cardiac arrest & resuscitation
Lower versus higher oxygen targets for out-of-hospital cardiac arrest: a systematic review and meta-analysis
Pooled resultResult — go to the resultRelative risk 0.97 95% CI 0.82–1.14Authors' conclusion
Lower oxygen target did not reduce the mortality compared with higher oxygen target in patients after out-of-hospital cardiac arrest.
Study context
- Population
- Adults (aged ≥ 18 years) after OHCA
- Participants
- 1,451 adults · 7 RCTs
- Comparison
- Lower vs higher oxygen target
- Outcome
- Mortality
- Follow-up
- 90 days after cardiac arrest
Methodological detailstrial sequential analysis, GRADE approach
- Trial sequential analysis
- GRADE approach
Pooled result
As reported in the abstract
Relative risk
0.97
95% CI 0.82–1.14
Higher oxygen target vs Lower oxygen target
RR 0.97 (95% CI 0.82–1.14)
Further pooled results
Trial sequential, subgroup and sensitivity analyses
- Findings were robust
Original publication
Lower versus higher oxygen targets for out-of-hospital cardiac arrest: a systematic review and meta-analysis. Crit Care. Published 19 October 2023. doi:10.
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