Cardiothoracic & vascular anaesthesia
Lowest Measured Temperature and Adverse Outcomes After Cardiac Surgery: Analysis of the Society of Thoracic Surgeons Adult Cardiac Surgery Database
Authors' conclusion
Hypothermia during CPB did not alter the risk of postoperative stroke. Secondary outcomes varied in their directionality of association with temperature, indicating that certain cardiac surgery patients may benefit, but others could be harmed by routine therapeutic hypothermia during CPB.
Study context
- Population
- Adults undergoing CABG, valve surgery or combined CABG-valve procedures with cardiopulmonary bypass (CPB), STS Adult Cardiac Surgery Database, July 1, 2011–March 1, 2022
- Participants
- 1,847,808 adults
- Exposure
- Lowest measured temperature during CPB, as a continuous variable
- Outcome
- Postoperative stroke
Methodological detailspropensity score-weighted regression analysis, registry (STS Adult Cardiac Surgery Database)
- Propensity score-weighted regression analysis
- Registry (STS Adult Cardiac Surgery Database)
Main finding
As reported in the abstract
- No association between lowest measured temperature (LMT) and postoperative stroke
- P =0.316
Observational data: associations, not effects.
Secondary outcomes
Encephalopathy or coma
- Not associated with lower LMT
- P = 0.649
30-day mortality
- Not associated with lower LMT
- P = 0.691
AKI
- Less common with lower and more common with higher LMTs
- P < 0.001
Pneumonia
- Less common with higher LMTs
- P = 0.002
Safety
Reoperation for bleeding
- More common with higher LMTs
- P < 0.001
Original publication
Lowest Measured Temperature and Adverse Outcomes After Cardiac Surgery: Analysis of the Society of Thoracic Surgeons Adult Cardiac Surgery Database. Ann Surg. Published 26 March 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →