Cardiothoracic & vascular anesthesia
Variations in perioperative management and outcomes of patents undergoing coronary artery bypass grafting by sex, race, and ethnicity: analysis of a US cardiac surgery database
Authors' conclusion
There is variability in CABG anaesthetic practices by sex, race, and ethnicity.
Study context
- Population
- Patients undergoing isolated Coronary Artery Bypass Graft (CABG), Society of Thoracic Surgeons Adult Cardiac Surgery Database, July 2017 to December 2023
- Participants
- 40,009 patients
- Exposure
- Anaesthetic practices by sex, race and ethnicity; anaesthetic practices and postoperative morbidity and mortality
- Outcome
- Association of key anaesthetic practices (TOE, PAC, multimodal analgesia, acute normovolaemic haemodilution, transfusion algorithm, cerebral oximetry, EEG, anaesthesia care team) with sex, race and ethnicity
Methodological detailsmultivariable models, registry database
- Multivariable models
- Registry database
Main finding
As reported in the abstract
Receipt of anaesthetic practices
Odds ratio (95% CI)P value
Black vs Whitereceipt of TOE
0.78(0.71–0.86)
P < 0.001Black vs Whitereceipt of PAC
0.84(0.73–0.91)
P < 0.008Female vs Malereceipt of MMA
0.82(0.71–0.96)
P = 0.011Black vs Whitereceipt of MMA
0.58(0.50–0.68)
P < 0.001- Female vs Male · receipt of TOE
- OR 0.86; P < 0.001
Observational data: associations, not effects.
Further findings
Postoperative morbidity and mortality by anaesthetic practice
| OR (95% CI) | P value | ||
|---|---|---|---|
| TOEImproved outcomes · independently associated | 0.88 (0.78–1.00) | P < 0.047 | |
| MMAImproved outcomes · independently associated | 0.76 (0.65–0.88) | P < 0.001 | |
| PACWorse outcomes · independently associated | 1.25 (1.15–1.36) | P < 0.001 | |
| Anaesthesia attending with fellow/resident teamWorse outcomes · independently associated | 1.30 (1.18–1.43) | P < 0.001 | |
| 0.512Odds ratio (log scale) |
Original publication
Variations in perioperative management and outcomes of patents undergoing coronary artery bypass grafting by sex, race, and ethnicity: analysis of a US cardiac surgery database. Br J Anaesth. Published 29 October 2025. doi:10. 1016/ j. bja. 2025. 08. 047
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