Cardiothoracic & vascular anesthesia

Variations in perioperative management and outcomes of patents undergoing coronary artery bypass grafting by sex, race, and ethnicity: analysis of a US cardiac surgery database

Br J AnaesthPublished Retrospective cohort study

Authors' conclusion

There is variability in CABG anaesthetic practices by sex, race, and ethnicity.

Study context

Population
Patients undergoing isolated Coronary Artery Bypass Graft (CABG), Society of Thoracic Surgeons Adult Cardiac Surgery Database, July 2017 to December 2023
Participants
40,009 patients
Exposure
Anaesthetic practices by sex, race and ethnicity; anaesthetic practices and postoperative morbidity and mortality
Outcome
Association of key anaesthetic practices (TOE, PAC, multimodal analgesia, acute normovolaemic haemodilution, transfusion algorithm, cerebral oximetry, EEG, anaesthesia care team) with sex, race and ethnicity
Methodological detailsmultivariable models, registry database
  • Multivariable models
  • Registry database

Main finding

As reported in the abstract

Receipt of anaesthetic practices
Odds ratio (95% CI)P value
Black vs Whitereceipt of TOE
0.78(0.71–0.86)
P < 0.001
Black vs Whitereceipt of PAC
0.84(0.73–0.91)
P < 0.008
Female vs Malereceipt of MMA
0.82(0.71–0.96)
P = 0.011
Black vs Whitereceipt of MMA
0.58(0.50–0.68)
P < 0.001
Female vs Male · receipt of TOE
OR 0.86; P < 0.001

Observational data: associations, not effects.

Further findings

Postoperative morbidity and mortality by anaesthetic practice

OR (95% CI)P value
TOEImproved outcomes · independently associated0.88 (0.78–1.00)P < 0.047
MMAImproved outcomes · independently associated0.76 (0.65–0.88)P < 0.001
PACWorse outcomes · independently associated1.25 (1.15–1.36)P < 0.001
Anaesthesia attending with fellow/resident teamWorse outcomes · independently associated1.30 (1.18–1.43)P < 0.001

Original publication

Variations in perioperative management and outcomes of patents undergoing coronary artery bypass grafting by sex, race, and ethnicity: analysis of a US cardiac surgery database. Br J Anaesth. Published 29 October 2025. doi:10.1016/j.bja.2025.08.047

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