Cardiothoracic & vascular anesthesia

Surgical Volume and Outcomes of Intraoperative Transesophageal Echocardiography in Coronary Artery Bypass Grafting

JAMA Netw OpenPublished Matched retrospective cohort study

Authors' conclusion

In isolated CABG, intraoperative TEE was associated with survival benefit at low- and medium-volume hospitals, particularly in patients with complex coronary disease or hemodynamic instability, but not at high-volume hospitals.

Study context

Population
Patients aged 18 years or older who underwent isolated coronary artery bypass graft (CABG) surgery between July 1, 2014, and June 30, 2022, at low, medium and high surgical volume hospitals61.8% received transesophageal echocardiography (TEE)
Participants
1,266,055 patients
Exposure
Intraoperative TEE vs without TEE during isolated CABG
Outcome
Mortality within 30 days of surgery
Follow-up
30 days
Methodological details2-stage, target trial emulation, stratified by hospital surgical volume, Society of Thoracic Surgeons (STS) Adult Cardiac Surgery Database, Data analysis August 8, 2023, to December 15, 2024
  • 2-stage
  • Target trial emulation
  • Stratified by hospital surgical volume
  • STS Adult Cardiac Surgery Database
  • Data analysis August 8, 2023, to December 15, 2024

Main finding

As reported in the abstract

30-day mortality by hospital surgical volume (subgroup)

TEE

Low volume
2.47%
Medium volume
2.09%
High volume
1.72%

Without TEE

Low volume
2.94%
Medium volume
2.34%
High volume
1.77%

Low volume

TEE2.47%
Without TEE2.94%

Medium volume

TEE2.09%
Without TEE2.34%

High volume

TEE1.72%
Without TEE1.77%
TEE vs Without TEEOdds ratio (95% CI)P value
Low surgical volume
0.83(0.78–0.89)
P < 0.001
Medium surgical volume
0.89(0.85–0.93)
P < 0.001
High surgical volume
0.97(0.91–1.03)
P = 0.48

Observational data: associations, not effects.

Further findings

Patient subpopulations at low and medium volume hospitals (subgroup)

Greatest TEE survival benefit with >50% (vs ≤50%) left-main stenosis, ≥3 (vs <3) diseased coronaries, and preoperative inotropic requirement

Original publication

Surgical Volume and Outcomes of Intraoperative Transesophageal Echocardiography in Coronary Artery Bypass Grafting. JAMA Netw Open. Published 1 October 2025. doi:10.1001/jamanetworkopen.2025.40559

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