Respiratory failure & ventilation

Lung- and diaphragm-protective mechanical ventilation in acute respiratory distress syndrome

Intensive Care MedPublished Narrative review

An erratum to this article was published (Intensive Care Med, Oct 2026 ↗)

Study context

Population
Patients with acute respiratory distress syndrome (ARDS) on mechanical ventilation

Main finding

As reported in the abstract

  • Excessive respiratory effort may further damage injured lungs and lead to diaphragm myotrauma (experimental and observational data)
  • Insufficient effort and prolonged passive ventilation associated with diaphragm atrophy and dysfunction
  • Lung- and diaphragm-protective (LDP) framework: integrate ventilation and sedation strategies to facilitate timely and safe spontaneous breathing
  • Emerging modalities: diaphragm neurostimulation and partial NMB

Original publication

Lung- and diaphragm-protective mechanical ventilation in acute respiratory distress syndrome. Intensive Care Med. Published 7 July 2026. doi:10.1007/s00134-026-08535-x

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.