Respiratory failure & ventilation
Lung perfusion estimation by saline-contrast electrical impedance tomography (EIT) without breath hold: a randomized cross-over trial
Authors' conclusion
The non-apnea contrast-EIT method provides consistent lung perfusion images with the conventional apnea method, expanding EIT applicability to patients intolerant to apnea and potentially yielding more physiologically realistic results.
Study context
- Population
- Mechanically ventilated ICU patientsin final analysis
- Participants
- 20 participants
- Comparison
- Non-apnea vs apnea saline-contrast EIT
- Primary endpoint
- Pixel-wise perfusion correlation between apnea and non-apnea methods (Spearman)
Primary result
As reported in the abstract
Pixel-wise perfusion correlation, apnea vs non-apnea
Spearman r, median (IQR 0.90-0.97); good overall consistency
0.94
Further findings
Impedance drop duration · significantly shorter with non-apnea
P = 0.008
Global V/Q match%, dead space%, shunt%
- Comparable between the two methods
Original publication
Lung perfusion estimation by saline-contrast EIT without breath hold: a randomized cross-over trial. Crit Care. Published 5 January 2026. doi:10. 1186/ s13054-025-05823-8
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