Respiratory failure & ventilation

Lung perfusion estimation by saline-contrast electrical impedance tomography (EIT) without breath hold: a randomized cross-over trial

Crit CarePublished Randomised cross-over trial

Authors' conclusion

The non-apnea contrast-EIT method provides consistent lung perfusion images with the conventional apnea method, expanding EIT applicability to patients intolerant to apnea and potentially yielding more physiologically realistic results.

Study context

Population
Mechanically ventilated ICU patientsin final analysis
Participants
20 participants
Comparison
Non-apnea vs apnea saline-contrast EIT
Primary endpoint
Pixel-wise perfusion correlation between apnea and non-apnea methods (Spearman)

Primary result

As reported in the abstract

Pixel-wise perfusion correlation, apnea vs non-apnea

Spearman r, median (IQR 0.90-0.97); good overall consistency

0.94

Further findings

Impedance drop duration · significantly shorter with non-apnea

P = 0.008

Global V/Q match%, dead space%, shunt%

Comparable between the two methods

Original publication

Lung perfusion estimation by saline-contrast EIT without breath hold: a randomized cross-over trial. Crit Care. Published 5 January 2026. doi:10.1186/s13054-025-05823-8

Composed by AI from the published abstract and checked against it. How Briefs are made →

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