Respiratory failure & ventilation

Lung Ultrasound Prediction Model for Acute Respiratory Distress Syndrome: A Multicenter Prospective Observational Study

Am J Respir Crit Care MedPublished Diagnostic accuracy study

Authors' conclusion

The LUS-ARDS score can be used to accurately diagnose ARDS also after external validation.

Study context

Population
Invasively ventilated ICU patients
Comparison
LUS-ARDS score vs CXR, against expert panel acute respiratory distress syndrome (ARDS) diagnosis
Outcome
Diagnosis of ARDS
Methodological detailsmulticentre, prospective observational, derivation and external validation cohorts
  • Multicentre
  • Prospective observational
  • Derivation and external validation cohorts

Performance

As reported in the abstract

Test or modelAUC, certain patients of derivation cohort (n=324) (95% CI 0.85-0.95)AUC, all patients of validation cohort (n=129) (95% CI 0.72-0.87)
LUS-ARDS score0.900.80

LUS-ARDS score

AUC, certain patients of derivation cohort (n=324) (95% CI 0.85-0.95)0.90
AUC, all patients of validation cohort (n=129) (95% CI 0.72-0.87)0.80

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Lung Ultrasound Prediction Model for Acute Respiratory Distress Syndrome: A Multicenter Prospective Observational Study. Am J Respir Crit Care Med. Published 15 June 2023. doi:10.1164/rccm.202210-1882oc

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