Perioperative medicine & outcomes
Management of Patients Receiving Antiplatelet Therapy During Gastroenterological Surgery: A Multicenter Prospective Cohort Study (GSATT)
Authors' conclusion
APT discontinuation after elective gastroenterological surgery increases the risk of thromboembolic consequences, whereas continuing preoperative aspirin greatly reduces this risk.
Study context
- Population
- Patients undergoing gastroenterological surgery, including patients receiving antiplatelet therapy (APT), 14 centres, October 2019–December 2021GSATT study
- Participants
- 1,170 patients
- Exposure
- Continued vs discontinued preoperative aspirin APT vs non-APT
- Outcome
- Thromboembolic complications
Methodological detailsmulticentre, propensity-score matched
- Multicentre
- Propensity-score matched
Main finding
As reported in the abstract
P = 0.027
Observational data: associations, not effects.
Further findings
| Outcome | Continued-APT | Discontinued-APT | P value |
|---|---|---|---|
| Thromboembolic complications, propensity-matchedContinued-APT vs Discontinued-APT · propensity score matched | 0.6% | 3.3% | P = 0.012 |
Independent risk factors for postoperative thromboembolism (multivariate, entire cohort)
- Discontinuation of APT
- P < 0.001
- Chronic anticoagulant use
- P < 0.001
Original publication
Management of Patients Receiving Antiplatelet Therapy During Gastroenterological Surgery: A Multicenter Prospective Cohort Study (GSATT). Ann Surg. Published 23 October 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →