ICU sedation, delirium & recovery

Mental health outcomes at intensive care unit discharge: prevalence, mediators and risk factors

Ann Intensive CarePublished Prospective observational study

Authors' conclusion

Psychological disorders are common at ICU discharge, mediated by peritraumatic distress, and associated with identifiable risk factors.

Study context

Population
Intensive Care Unit (ICU) patients at ICU discharge, admitted January 2023–April 2024
Participants
243 patients
Outcome
Prevalence of psychological disorders at ICU discharge (DICS-M: Discharge Intensive Care Syndrome - Mental component)
Follow-up
ICU discharge

Main finding

As reported in the abstract

DICS-M prevalence

Prevalence of DICS-M

53%

95% CI 46–59

Acute stress

37%

Anxiety

36%

Depression

23%

Observational data: associations, not effects.

Further findings

Mediators of DICS-M

Peritraumatic distress was the main mediator of DICS-M

Risk factors of DICS-M

Female gender and history of psychiatric and cardiac conditions identified as risk factors (univariate and multivariable analyses)

Original publication

Mental health outcomes at intensive care unit discharge: prevalence, mediators and risk factors. Ann Intensive Care. Published 25 September 2025. doi:10.1186/s13613-025-01545-w

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